Table 2.
Top Twenty Genes Overexpressed by the Supportive Feeder Layer
| |
|
Fold difference |
|
|---|---|---|---|
| Gene | Accession No. | SDEC/Detroit 551 | SDEC/WI38 |
| Prostaglandin-endoperoxide synthase | NM_000963 | 26.37 | 230.22 |
| Adhesion molecule with Ig-like domain | AC004010 | 27.10 | 180.58 |
| Prostaglandin I2 (prostacyclin) synthase | NM_000961 | 24.09 | 161.50 |
| Cytochrome P450, family 1, subfamily B, polypeptide 1 | AU144855 | 13.49 | 151.47 |
| Serglycin | NM_002727 | 24.26 | 122.90 |
| Interleukin 8 | AF043337 | 21.75 | 87.01 |
| Protocadherin 10 | AI640307 | 7.66 | 94.38 |
| ADAM metallopeptidase domain 12 | NM_003474 | 5.18 | 60.66 |
| CDNA FLJ44429 | AI088063 | 6.73 | 52.08 |
| Ras-related associated with diabetes | NM_004165 | 39.78 | 8.38 |
| Serum/glucocorticoid regulated kinase | NM_005627 | 11.58 | 31.28 |
| Chemokine (C-C motif) ligand 2 | S69738 | 9.45 | 27.56 |
| Cadherin 2, type 1, N-cadherin | M34064 | 8.47 | 27.39 |
| Tumor necrosis factor superfamily, member 4 | NM_003326 | 24.37 | 7.15 |
| Dipeptiyl-peptidase 4 (CD26) | M74777 | 6.38 | 24.38 |
| Leukemia inhibitory factor | NM_002309 | 21.17 | 5.50 |
| Coiled-coil domain containing 80 | AA570507 | 5.06 | 21.35 |
| HEG homolog 1 | AI148659 | 6.85 | 17.14 |
| Aldehyde dehydrogenase 1 family, member A3 | NM_000693 | 5.30 | 18.61 |
| Chromosome 3 ORF | AU157304 | 5.40 | 13.94 |