Table 2.
Correlation of BRG1 binding with H3K4me3 and H3K27me3a
| Comparison | Correlation (R2) |
|---|---|
| BRG1 vs H3K4me3 | 0.11 |
| BRG1 vs H3K27me3 | 0.002 |
a
For each gene, the amount of BRG1 binding and the level of histone methylation were compared. The number of sequence reads in statistically significant regions was determined using CisGenom and summed using Excel for BRG1, H3K4me3, and H3K27me3 in Th2S cells. BRG1 data were from this study; HeK4me3 and H3K27me3 data were previously published (85). Linear curve fit was determined by least-squares regression. H3K4me3 is a marker for active promoters, while H3K27me3 marks a subset of repressed genes.