Table 1.

HCNEs

Region	Human/chicken alignment		Transcriptional activitya	Corresponding region in:		No. of embryos showing Lacz expression/total no. examined
	Length (bp)	% identity		Alvarez-Medina et al. (3)	Abassi et al. (2)
1	229	61	Strong; DV gradient			40/53
2	132	83.3	Strong; DV gradient			10/10
3	406	68.5	Negative			5/6
4	455	79.8	Strong; continuous	HCNR1; weak expression in neural tube		17/23
5	720	87.4	Moderate; DV gradient	HCNR1; weak expression in neural tube	CNE12; not tested in vivo	9/14
6	244	61.5	Strong; DV gradient	HCNR1; weak expression in neural tube		12/20
7	542	79.9	Moderate; AP gradient	HCNR1; weak expression in neural tube		3/9
8	214	64.5	Moderate; DV gradient			6/8
9	226	61.9	Strong; DV gradient			13/34
10	203	80.3	Negative			1/6
11	111	62.2	No activity			11/12
12	355	69	No activity			5/8
13	483	89.6	Strong; DV gradient	HCNR2; strong expression in neural tube	CNE1; anterior CNS in zebrafish	6/9
14	487	90.1	Strong; DV gradient	HCNR2; strong expression in neural tube	CNE1; anterior CNS in zebrafish	6/9
15	229	76.9	Moderate; DV gradient	HCNR2; strong expression in neural tube		10/13
16	271	67.5	Weak; posterior			4/5
17	98	78.6	Weak; dorsal			5/7
18	1,090	93.1	Strong; excluded from floor plate	HCNR3; moderate expression in neural tube	CNE2; anterior CNS in zebrafish and mouse	11/11
19	433	71.1	Weak			3/7

^aAP, anteroposterior; DV, dorsoventral.