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. 2011 Jul;138(1):117–130. doi: 10.1085/jgp.201010586

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© 2011 Clausen et al.

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Figure 5. — Effects of salbutamol on tetanic force in soleus obtained from WT and mutant mice. Muscles were stimulated using 2-s 120-Hz trains of 0.2-ms pulses at 7 V in the presence of 10⁻⁵ M tubocurarine and salbutamol at the concentrations indicated. Each point represents the mean of observations on four muscles, with error bars denoting SEM. In the absence of salbutamol, the difference between tetanic force in WT and mutants was highly significant (P < 0.001). In the mutant muscles, salbutamol induced a significant increase in tetanic force at 10⁻⁸ M (P < 0.05), 10⁻⁷ M (P < 0.001), and 10⁻⁶ M (P < 0.001).