Table 3.
MCNs (n = 168) | Branch-duct IPMNs (n = 159) | P value | |
---|---|---|---|
Median age, y (range) | 44.5 (16–82) | 66 (35–90) | .0001 |
Sex (%) | |||
Female | 160 (95) | 91 (57) | .0001 |
Male | 8 (5) | 68 (43) | |
Family history of pancreatic cancer (%) | |||
Yes | 6 (3.5) | 16 (11) | .01 |
No | 162 (96.5) | 126 (89) | |
History of other neoplasm (%) | |||
Yes | 15 (9) | 32 (20) | .006 |
No | 153 (91) | 127 (80) | |
Tumor site (%) | |||
Proximal | 5 (3) | 82 (52) | .0001 |
Distal | 163 (97) | 40 (25) | |
Multifocal lesions | 0 | 37 (23) | |
Incidental diagnosis (%) | |||
Yes | 46 (27.5) | 55 (34.5) | .1 |
No | 122 (72.5) | 104 (65.5) | |
Abdominal pain (%)a | |||
Yes | 104 (62) | 72 (45) | .004 |
No | 64 (38) | 87 (55) | |
Presence of other symptoms (%)a | |||
Yes | 44 (26%) | 72 (45%) | .0001 |
No | 124 (74%) | 87 (65%) | |
Jaundice | 1 (0.5) | 7 (5) | .06 |
Diabetes | 9 (5.5) | 14 (9) | .3 |
Weight loss | 27 (16) | 37 (23) | .1 |
Acute pancreatitis | 9 (5.5) | 27 (17) | .001 |
Pathology (%) | |||
Adenoma | 122 (73) | 71 (44) | .0001 |
Borderline | 17 (10) | 54 (34) | .001 |
Carcinoma in situ | 10 (6) | 17 (11) | .2 |
Invasive carcinoma | 19 (11) | 17 (11) | .8 |
Median tumor size, mm (range) | 49 (8–150) | 20 (5–100) | .0001 |
Presence of lymph node metastases (%)b | 0 | 4 (23.5) | .08 |
Some patients complained of more than 1 symptom.
Rate of lymph node metastases was calculated considering only patients with invasive cancer.