Table 9.
Cation/proton antiporters identified in L. hongkongensis, N. meningitidis, N. gonorrhoeae and C. violaceum; and the model bacterial organisms, B. subtilis and E. coli
| Features | L. hongkongensis HLHK9 | N. meningitidis MC58b | N. gonorrhoeae FA 1090b | C. violaceum ATCC12472 | B. subtilis 168b | E. coli K12-MG1655b |
|---|---|---|---|---|---|---|
| Genome size (Mb)a | 3.17 | 2.27 | 2.15 | 4.75 | 4.22 | 4.64 |
| Total no. of transporter proteins | 442 | 103 | 96 | 564 | 298 | 354 |
| No. of identified transporters per Mb genome | 139 | 45.4 | 44.7 | 119 | 71.0 | 76.3 |
| No. of cation/proton antiporters | 6 | 4 | 4 | 3 | 6 | 7 |
| Monovalent cation:proton antiporter-1 (CPA1) family | 0 | 1 | 1 | 0 | 1 | 2 |
| Monovalent cation:proton antiporter-2 (CPA2) family | 4 | 1 | 1 | 3 | 2 | 3 |
| Monovalent cation (K+ or Na+):proton antiporter-3 (CPA3) family | 0 | 0 | 0 | 0 | 1c | 0 |
| NhaA Na+:H+ antiporter family | 0 | 0 | 0 | 0 | 0 | 1 |
| NhaB Na+:H+ antiporter family | 0 | 0 | 0 | 0 | 0 | 1 |
| NhaC Na+:H+ antiporter family | 2 | 2 | 2 | 0 | 2 | 0 |
| NhaD Na+:H+ antiporter family | 0 | 0 | 0 | 0 | 0 | 0 |
aGenome size data obtained from www.ncbi.nlm.nih.gov/projects/genome/, calculations based on data from www.membranetransport.org and with updated number of transporters in our annotation
bRetrieved from www.membranetransport.org
cNot listed on www.membranetransport.org, see Krulwich et. al.