Table 9.
ATP, NADH, NADPH, and CoQ10 The average levels measured in the Autism and Neurotypical groups are reported below, along with their standard deviations
| Units | Autism Group | Neuro-typical Group | % Difference | p-value | Neurotypical Reference Range (10th and 90th percentiles) | Autism Group % below RR | Autism Group % above RR | |
|---|---|---|---|---|---|---|---|---|
| ATP (plasma) |
nmol/l |
14.5 +/- 4.2 |
18.5 +/- 4.8 |
-22% | < 0.0001 * | 13.21 | 36% | 4% |
| NADH (RBC) |
nmol/ml |
15.3 +/- 4.1 |
20.7 +/- 4.3 |
-26% | < 0.0001 * | 16-25 | 51% | 2% |
| NADPH (RBC) |
nmol/ml |
22.6 +/- 6.1 |
30.9 +/- 8.5 |
-27% | < 0.0001 * | 20-40 | 37% | 2% |
| CoQ10 (plasma) |
μg/ml | 0.55 +/- 0.15 |
0.60 +/- 0.16 |
n.s. | 0.4-0.8 | 9% | 2% | |
The p-value for a t-test comparison of the two groups is also reported. If the p-value is below 0.05, then the % difference between the groups is reported, and the result is highlighted.
The table also lists the reference range of the neurotypical group (10th and 90th percentiles), and the % of the Autism group who are above or below the reference ranges. Note that if the groups were identical, 10% would be above and 10% would be below. Percentages above 25% are highlighted.
* Statistically significant difference between the two groups with 95% confidence per Bonferroni analysis.