Table 1.
CVT n = 39 (16.3%) |
No CVT n = 200 (83.7%) |
p | |
---|---|---|---|
Age (y) | 43.9 | 42.5 | 0.73 |
Sex | 0.93 | ||
Males | 12 (31%) | 57 (29%) | |
Females | 27 (69%) | 143 (71%) | |
Imaging | |||
MRI/MRA | 30 (77%) | 158 (79%) | 0.94 |
CTA | 12 (31%) | 49 (24%) | 0.62 |
Symptoms/History | |||
Headaches | 27 (69%) | 145 (73%) | 0.83 |
- acute (≤ 1day) | 2 (5%) | 34 (17%) | 0.09 |
- subacte (> 1 day) | 25 (64%) | 111 (56%) | 0.41 |
- unilateral | 7 (18%) | 30 (15%) | 0.63 |
Seizure (focal or generalized) | 11 (28%) | 19 (10%) | 0.003 |
Focal neurological deficit | 17 (44%) | 68 (34%) | 0.33 |
Papilledema | 4 (10%) | 4 (4%) | 0.15 |
Disturbed consciousness | 0 (0%) | 10 (5%) | 0.32 |
Pregnancy* | 3 (11%) | 12 (8%) | 0.43 |
Previous venous thrombosis | 5 (13%) | 24 (12%) | 0.90 |
Oral contraceptives* | 6 (22%) | 29 (20%) | 0.49 |
D-Dimer measurement | 29 (74%) | 69 (35%) | 0.001 |
Increased§ | 22 (76%) | 6 (9%) | 0.001 |
Absolute values (μg/ml), median (range) | 0.21 (0.09 - 2.51) | 0.07 (0.01 - 3.1) | 0.001 |
Thrombus location | Not applicable | ||
Superior sagittal sinus | 14 (36%) | ||
Transverse sinus | 24 (83%) | ||
Sigmoid sinus | 6 (21%) | ||
Internal jugular vein | 3 (10%) | ||
Straight sinus | 10 (34%) | ||
Cortical veins | 1 (3%) |
* limited to females.
§ limited to patients with D-dimer measurements, reference range below 0.19 μg/ml.