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. 2011 Jun 25;11:272. doi: 10.1186/1471-2407-11-272

Table 2.

Risk factors for lung cancer for HIV patients and population controls

Lung cancer (HIV/population controls), N Unadjusted IRR (95% CI) Adjusted IRR* (95% CI)
All 29/183 2.08 (1.41 - 3.08) 2.38 (1.61 - 3.53)

Stratification

Male gender* 27/156 2.33 (1.55 - 3.50) 2.66 (1.77 - 4.01)
Female gender 2/27 0.91 (0.22 - 3.82) **
Native 24/179 2.13 (2.39 - 3.27) 2.56 (1.47 - 3.46)
Immigrant 5/4 6.38 (1.71 - 23.86) **
Younger than or 50 years at index date 18/104 2.33 (1.35 - 4.04) 2.34 (1.35 - 4.06)
Older than 50 years at index date * 14/98 2.07 (1.18 - 3.63) 2.08 (1.19 - 3.65)
HIV diagnosed before 1995 18/112 2.34 (1.42 - 3.85) 2.60 (1.58 - 4.28)
HIV diagnosed after 1995 at index date 11/71 1.75 (0.93 - 3.31) 2.13 (1.12 - 4.03)
Smoker or former smoker in any quantity 29/81 3.79 (2.48 - 5.97) 4.06 (2.66 - 6.21)
Never smoked 0/35 ** **
Route of HIV infection
 Men who have sex with men (MSM) 12/99 1.60 (0.88 - 2.91) 1.82 (0.99 - 3.12)
 Heterosexually infected men 12/44 3.40 (1.80 - 6.45) 4.19 (2.20 - 7.96)
 Heterosexually infected women 2/18 1.26 (0.30 - 5.44) **
 Injection drug user (IDU) 3/13 1.95 (1.28 - 2.94) **
Baseline CD4 < 350 cells/μL or AIDS defining event at index date 20/111 2.70 (1.68 - 4.35) 3.25 (2.01 - 5.24)
Baseline CD4 350 cells/μL and no AIDS defining event at index date 6/40 1.68 (0.71 - 3.96) 1.71 (0.72 - 4.03)

* All adjusted for gender and age, except the stratification on male which is only adjusted for age and age > 50 which is only adjusted for gender.

** Too few events for analysis.