Table 2.
Lung cancer (HIV/population controls), N | Unadjusted IRR (95% CI) | Adjusted IRR* (95% CI) | |
---|---|---|---|
All | 29/183 | 2.08 (1.41 - 3.08) | 2.38 (1.61 - 3.53) |
Stratification | |||
Male gender* | 27/156 | 2.33 (1.55 - 3.50) | 2.66 (1.77 - 4.01) |
Female gender | 2/27 | 0.91 (0.22 - 3.82) | ** |
Native | 24/179 | 2.13 (2.39 - 3.27) | 2.56 (1.47 - 3.46) |
Immigrant | 5/4 | 6.38 (1.71 - 23.86) | ** |
Younger than or 50 years at index date | 18/104 | 2.33 (1.35 - 4.04) | 2.34 (1.35 - 4.06) |
Older than 50 years at index date * | 14/98 | 2.07 (1.18 - 3.63) | 2.08 (1.19 - 3.65) |
HIV diagnosed before 1995 | 18/112 | 2.34 (1.42 - 3.85) | 2.60 (1.58 - 4.28) |
HIV diagnosed after 1995 at index date | 11/71 | 1.75 (0.93 - 3.31) | 2.13 (1.12 - 4.03) |
Smoker or former smoker in any quantity | 29/81 | 3.79 (2.48 - 5.97) | 4.06 (2.66 - 6.21) |
Never smoked | 0/35 | ** | ** |
Route of HIV infection | |||
Men who have sex with men (MSM) | 12/99 | 1.60 (0.88 - 2.91) | 1.82 (0.99 - 3.12) |
Heterosexually infected men | 12/44 | 3.40 (1.80 - 6.45) | 4.19 (2.20 - 7.96) |
Heterosexually infected women | 2/18 | 1.26 (0.30 - 5.44) | ** |
Injection drug user (IDU) | 3/13 | 1.95 (1.28 - 2.94) | ** |
Baseline CD4 < 350 cells/μL or AIDS defining event at index date | 20/111 | 2.70 (1.68 - 4.35) | 3.25 (2.01 - 5.24) |
Baseline CD4 ≥ 350 cells/μL and no AIDS defining event at index date | 6/40 | 1.68 (0.71 - 3.96) | 1.71 (0.72 - 4.03) |
* All adjusted for gender and age, except the stratification on male which is only adjusted for age and age > 50 which is only adjusted for gender.
** Too few events for analysis.