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. Author manuscript; available in PMC: 2012 May 19.
Published in final edited form as: J Am Chem Soc. 2010 Nov 19;132(49):17411–17425. doi: 10.1021/ja9067035

Figure 2. Lysine acetylation decreases the thermostability of BCA II.

Figure 2

A) Thermal denaturation of unacetylated BCA II (denoted Ac(0)), partially acetylated BCA II (Ac(~6) and Ac(~9)) and peracetylated BCA II (Ac(18)) measured by differential scanning calorimetry (DSC). Integration of peaks produced melting temperature (Tm) values of 69.3 °C (Ac(0)), 65.7 °C (Ac(~6)), 63.9 °C (Ac(~9)), and 49.8 °C (Ac(18)). B) Plot of Tm of Ac(0), Ac(~6), Ac(~9), Ac(18) versus the average number of modifications.