Table 6.

Patient Characteristics and Overall Survival (n = 863)

Variable	No. of patients	No. of deaths (%)	MST (months)	P (log-rank)
Age (years)				0.292
≤50	111	84 (76)	15.4
51–60	254	185 (73)	13.9
61–70	322	219 (68)	14.7
>70	176	123 (69)	17.1
Sex				0.845
Female	342	250 (73)	15.5
Male	521	361 (69)	14.8
Tumor stage				<0.001
NED	20	10 (50)	46.7
Resectable	250	143 (57)	30.6
Locally advanced	201	156 (78)	14.4
Metastatic	373	289 (77)	9.5
Unstaged	19	13 (68)	19.3
Tumor resection				<0.001
Yes	284	155 (55)	39.1
No	579	456 (79)	10.8
Margin statusa				0.005
Negative	235	121 (51)	40.0
Positive	49	456 (79)	24.9
Lymph node statusa				<0.001
Negative	122	50 (41)	67.7
Positive	162	105 (65)	28.2
CA19-9 (units/mL)b				<0.001
≤47	192	107 (58)	26.4
48–500	326	232 (71)	17.2
501–1000	92	67 (73)	13.4
>1000	248	202 (81)	9.6
Tumor grade				<0.001
Well	33	19 (58)	26.5
Moderate	333	220 (66)	21.4
Poor	154	115 (75)	12.4
Unknown	343	257 (74)	12.2

MST, median survival time; NED, no evidence of disease.

^aData only available for 284 patients with resected disease.

^bMissing value in 5 patients.