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Allosteric properties of four different forms of GDH; human GDH (hGDH), human GDH with the antenna replaced by a loop found in bacterial GDH (Antenna-less hGDH), Tetrahymena GDH (tGDH), and Tetrahymena GDH with the antenna replaced with that found in human GDH (tGDH with hGDH antenna).
| hGDH | Antenna-less hGDH | tGDH | tGDH with hGDH antenna | |
|---|---|---|---|---|
| GTP inhibition | + | − | − | + |
| PalmCoA inhibition | + | − | + | + |
| ADP activation | + | − | + | + |
| Leucine activation | + | + | − | + |
