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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Antiviral Res. 2011 May 12;91(2):120–132. doi: 10.1016/j.antiviral.2011.05.003

Figure 4.

Figure 4

Metabolic profile of PSI-353661. Time course of formation of PSI-353661 metabolites was monitored in primary human hepatocytes treated with 5 μM [3H]-labeled PSI-353661 up to 24 hours (A). The earlier time points were shown by plotting the same graph up to 4 hours (B). Formation of the metabolites was followed in primary hepatocytes treated with varying concentrations of exogenous PSI-353661 for 4 hours and the amount on intracellular metabolites were plotted against concentration of exogenously added PSI-353661 (C).