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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Antiviral Res. 2011 May 12;91(2):120–132. doi: 10.1016/j.antiviral.2011.05.003

Table 7. Kinetic parameters for hGUK1-mediated phosphorylation.

Km (μM) kcat (s-1) kcat / Km (μM-1s-1)
GMP 19.1 ± 4.5 74.7 ±17.6 3.9
PSI-353222 64.9 ± 1.6 0.31 ± 0.03 0.005
PSI-353224 No activity

Values are reported as the mean ± S.D. from three independent experiments.