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BRP-39 regulation of CS-induced inflammation. Ten-week-old WT and BRR-39 null mice (BRP-39−/−) were exposed to CS or RA for 1, 3, and 6 months. The mice were killed, and bronchoalveolar lavage (BAL) total cells (A) and differential counts of macrophages at 3-month (3M) and 6-month (6M) time points (B) were measured. Values in A and B represent the mean ± SEM of evaluations in a minimum of five animals (*P < 0.05, **P < 0.01).
