Figure 1.
Total serum IgE levels in congenic C57B6–cystic fibrosis (CF) transmembrane conductance regulator (CFTR)−/− mice and their littermates after Aspergillus fumigatus (Af) sensitization and challenge. Mice were sensitized with 200 μg of Af crude extract dissolved in 100 μl of PBS on Days 1 and 14. Blood samples were collected on Day 32, 48 hours after the third aerosol Af challenge. Total serum IgE in the Af-sensitized mice was measured by ELISA. Data are shown as group averages (±SEM).