Table 4.

Look AHEAD: Major Benefits of Lifestyle Changes

Study goal	Intervention group	Usual care group	P value
Weight loss	8.6%	0.7%	<0.001
Increased fitness (after weight adjustment)	20.9% (15.9%)	5.8% (10.8)	<0.001 (<0.001)
C-reactive protein	−43.6%	−16.7%	<0.001
HbA1c (<7%)	26.4%	5.4%	<0.001
Blood pressure (<130/80 mmHg)	15.1%	7.0%	<0.001
LDL-C (<100 mg/dL)	6.7%	8.0%	0.340
All three cardiovascular risk factors	12.8%	6.5%	<0.001

Adapted from references 24 and 24a.

AHEAD, Action for Health in Diabetes; HbA1c, glycosylated hemoglobin; LDL-C, low-density lipoprotein cholesterol.