. Author manuscript; available in PMC: 2011 Jul 14.

Published in final edited form as: Development. 2006 Mar 22;133(9):1657–1671. doi: 10.1242/dev.02341

Table 4. Effect of concanamycin on the sidedness of the expression of Shh and Nodal left-side markers in chick.

	Expression	Left		Right		Bilateral		None

Gene	Treatment	n	%	n	%	n	%	n	%	χ²	P
Shh	Control	17	100%	0	0%	0	0%	0	0%
	Concanamycin	15	33%	3	7%	17	38%	10	22%	19.370	≪0.001
Nodal	Control	25	100%	0	0%	0	0%	0	0%
	Concanamycin	43	77%	0	0%	6	11%	7	13%	5.297	0.001

The laterality of expression of Shh and Nodal is significantly altered in chick embryos treated with the H⁺-V-ATPase inhibitors concanamycin or DCCD.