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. Author manuscript; available in PMC: 2011 Jul 14.
Published in final edited form as: Development. 2006 Mar 22;133(9):1657–1671. doi: 10.1242/dev.02341

Table 5. Effect of H+-V-ATPase inhibitors on the sidedness of the expression of Spaw, a left-side marker in zebrafish.

Expression Left Right Bilateral None




Gene Treatment n % n % n % n % χ2 P
Spaw Control 25 93% 1 4% 1 4% 0 0%
A16 17 45% 9 24% 12 32% 0 0% 13.787 ≪0.001
Control 22 92% 1 4% 1 4% 0 0%
Concanamycin 11 42% 9 35% 6 23% 0 0% 11.439 ≪0.001

The laterality Spaw expression is significantly altered in zebrafish larvae treated with the H+-V-ATPase inhibitors lobatomide A16 or concanamycin.