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. Author manuscript; available in PMC: 2011 Nov 12.
Published in final edited form as: Neuron. 2011 May 12;70(3):468–481. doi: 10.1016/j.neuron.2011.03.020

Figure 8. The Effect of ApNLG Autism-Linked Mutant Expressed in the Postsynaptic Motor Neuron on Intermediate-Term Facilitation and LTF.

Figure 8

An ApNLG mutant harboring R to C mutation at the analogous position in human NLG-3 R451C mutant linked to ASD was overexpressed in the postsynaptic motor neuron in sensory-to-motor neuron co-cultures. EPSPs were recorded from motor neurons in response to extracellular stimulation of sensory neurons before, 1 hr, and 24 hr after exposure to 5 × 5-HT (10 μM, 5 min). Changes in amplitudes are shown as a bar graph.