Table 1.

Chemical and Physical Analysis of Polymeric Precursors and Conjugates

conjugate	Mwa	Pdb	valencec	effective diameterd	PDIe
P-7Fab′1.4	34	1.16	1.4	10.8	0.070
P-3Fab′1.5	193	1.25	1.5	17.8	0.203
P-3Fab′2.9	193	1.25	2.9	21.3	0.19
P-3Fab′3.2	193	1.25	3.2	30.2	0.168
P-3Fab′8.9	193	1.25	8.6	38.7	0.174

^aMolecular weight average of polymeric precursor as determined by size exclusion chromatography.

^bPolydiversity, ratio of molecular weight averages given by weight average over number average.

^cValence of conjugate or Fab′ per polymer chain as determined by modified amino acid analysis (see Experimental Procedures).

^dEffective diameter of conjugates as determined by dynamic light scattering (DLS).

^eValue of polydispersity index of the diameter of the conjugate determined by DLS.