Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Jun 23;108(28):11554–11559. doi: 10.1073/pnas.1102600108

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Fig. 1. — AID-deficient new emigrant/transitional B cells display an unusual IgH repertoire. (A) VH gene-usage frequencies in new emigrant/transitional B cells are represented for 11 healthy control subjects and seven AID-deficient patients. Sequences from 353 healthy control and 189 AID-deficient single transitional B cells were pooled. (B) The increased VH4-34 gene usage in AID-deficient new emigrant/transitional B cells is further analyzed. The frequencies of long IgH CDR3s (>14 aa) and IgH CDR3s containing two or more positively charged aa are represented in C and D, respectively. Each diamond represents an individual; the average is shown with a bar. Statistically significant differences are indicated.