Skip to main content
. 2011 Jun 24;108(28):11602–11607. doi: 10.1073/pnas.1018559108

Fig. 2.

Fig. 2.

Inhibition of cleavage of VWF115 by the NTP. (A) Proteolysis of 6 μM VWF115 by 3.5 nM ADAMTS13 in the presence and absence of 1 mM NTP and NTP(Leu1603Ala). VWF115 cleavage is visualized by SDS/PAGE. (B) Inhibition of the initial rate of cleavage of 2.5 μM VWF115 by 1 nM ADAMTS13 in the presence of 0 to 1 mM NTP or NTP(Leu1603Ala). The initial rate of proteolysis was quantified using HPLC.