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. 2011 Jun 23;108(28):11560–11565. doi: 10.1073/pnas.1102571108

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Fig. 6. — Aicda⁻^/− immature/T1 B cells are resistant to BCR-induced apoptosis. The susceptibility of immature/T1 B cells from Aicda^+/+ and Aicda⁻^/− BM to anti-IgM Ab-induced apoptosis was compared in cell culture (31). BM cells from Aicda^+/+ and Aicda⁻^/− mice were cultured in triplicate in media containing various concentrations of anti-IgM (anti-μ) Ab for 24 h. The numbers of Aicda^+/+ (filled symbols) and Aicda⁻^/− (open symbols) immature/T1 B cells in each treatment are shown. Data shown represent the means ± SD from three independent experiments.