Table 1.
Parameters | Protein (mg g−1) | SOD (U mg−1) | Catalase (U mg−1) | Glutathione Peroxidase (nmol g−1) | GSH (U mg−1) | TBARS nmol |
---|---|---|---|---|---|---|
Stomach | ||||||
Healthy | 2.23c ± 0.16 | 092.9a ± 08 | 46.5c ± 4.6 | 28.6a ± 2.4 | 376.6c ± 37 | 0.82a ± 0.07 |
Ulcerated | 1.39a ± 0.16 | 201.3d ± 21 | 22.8a±2.1 | 68.6c ± 5.6 | 216.2a ± 23 | 2.16c ± 0.19 |
GRAE 100 mg kg−1 | 1.68a ± 0.16 | 161.6c ± 18 | 38.6b ± 3.4 | 32.4b ± 3.5 | 306.5b ± 32 | 1.12b ± 0.08 |
GRAE 200 mg kg−1 | 2.46b ± 0.23 | 136.4b,c ± 14 | 43.1b,c ± 4.5 | 26.9a ± 2.8 | 351.5c ± 34 | 0.91a ± 0.06 |
Lansoprazole | 2.13b ± 0.13 | 124.3b ± 14 | 44b,c ± 4.5 | 26.7a ± 2.3 | 325b,c ± 32 | 0.94a ± 0.08 |
Serum | ||||||
Healthy | 6.621a ± 0.51 | 112.3a ± 28 | 44.20c ± 4.9 | 0.221a ± 0.004 | 23.6c ± 3.0 | 0.165a ± 0.01 |
Ulcerated | 6.845a ± 0.53 | 264.6d ± 32 | 22.90a ± 3.1 | 0.286c ± 0.02 | 11.1a ± 1.8 | 0.326d ± 0.02 |
GRAE 100 mg kg−1 | 6.663a ± 0.62 | 186.8c ± 21 | 34.23b ± 3.6 | 0.293d ± 0.03 | 16.5b ± 1.7 | 0.264c ± 0.02 |
GRAE 200 mg kg−1 | 6.943a ± 0.61 | 148.6b ± 15 | 41.45c ± 4.3 | 0.254b ± 0.03 | 22.3b,c ± 2.3 | 0.186a,b ± 0.02 |
Lansoprazole | 6.632a ± 0.62 | 143.6b,c ± 16 | 36.82b ± 3.4 | 0.246a ± 0.02 | 18.8a ± 2.3 | 0.188b ± 0.01 |
Liver | ||||||
Healthy | 24.2c ± 0.31 | 261.5b ± 41 | 28.42d ± 3.1 | 0.32a ± 0.02 | 414c ± 51 | 0.98a ± 0.13 |
Ulcerated | 21.9a ± 0.23 | 142.4a ± 18 | 22.18b,c ± 2.6 | 0.58c ± 0.05 | 221a ± 26 | 2.41d ± 0.23 |
GRAE 100 mg kg−1 | 23.7b ± 0.27 | 196.6a ± 21 | 22.54b,c ± 2.4 | 0.45a,b ± 0.04 | 323b ± 33 | 1.98c ± 0.21 |
GRAE 200 mg kg−1 | 24.2b ± 0.23 | 266.7d ± 36 | 26.67a ± 2.4 | 0.46a ± 0.04 | 382a ± 36 | 1.45b ± 0.27 |
Lansoprazole | 23.7b ± 0.25 | 234.4c,d ± 24 | 24.62a ± 2.3 | 0.41a ± 0.03 | 325a ± 31 | 1.64b ± 0.21 |
Different letters “a” to “d” in the column represents that values are significantly different when compared between ulcer induced with healthy control and GRAE/lansoprazole-treated groups.