Table 3.
Gastric mucin and H+, K+-ATPase levels in healthy, ulcerated and protected rats (n = 6) mean ± SD.
| Group (n = 6) | Mucin content (mg g−1) | H+, K+-ATPase μmol Pi released mg−1 h−1 |
|---|---|---|
| Healthy | 62.05d ± 5.1 | 0.721a ± 0.02 |
| Swim stress-induced ulcer model | ||
| Swim stress induced | 18.42a ± 3.4 | 2.610d ± 0.21 |
| GRAE 100 mg kg−1 b.w. | 43.36b ± 3.6 | 1.316c ± 0.18 |
| GRAE 200 mg kg−1 b.w. | 48.41b,c ± 3.4 | 0.831a ± 0.14 |
| Lansoprazole 30 mg kg−1 b.w. | 35.14b ± 2.4 | 1.220b ± 0.12 |
| Ethanol stress-induced ulcer model | ||
| Ethanol stress induced | 22.37a ± 2.3 | 2.318c ± 0.24 |
| GRAE 100 mg kg−1 b.w. | 36.32b ± 3.6 | 1.213b ± 0.26 |
| GRAE 200 mg kg−1 b.w. | 46.54c ± 3.8 | 0.793a ± 0.08 |
| Lansoprazole 30 mg kg−1 b.w. | 33.23b,c ± 2.4 | 1.240b ± 0.12 |
Different letters “a” to “d” in the column represents that values are significantly different when compared between ulcer induced with healthy control and GRAE/lansoprazole-treated groups. Range was provided by Duncan multiple test at P < .05. aLess significant; bModerately significant; cVery significant and dMost significant.