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. 2011 Aug;25(8):2551–2562. doi: 10.1096/fj.10-177816

Figure 2.

Figure 2.

A) Expression of eGFP driven by Fgf23 promoter in BMSCs collected from WT, Hyp, Dmp1−/−, and Hyp/Dmp1−/− mice lacking 1 allele of Fgf23 (Fgf23+/−[eGFP]) and cultured in osteoblast differentiating medium for 3 wk. Expression is reported after 3 wk of culture, showing intrinsic increase of Fgf23 expression by nodule-embedded cells in all 3 mutant groups compared to WT. B) mRNA expression of Fgf23 in calvariae. Values are expressed as mean ± se percentage relative to WT; n = 5 mice/group. *P < 0.05 vs. WT control; 1-way ANOVA and post hoc Fisher test.