Table 2.
The effect of excoecarianin against HSV-2 infectivity.
Concentration (μM) | Percentage control of viral infectivity | |
---|---|---|
Control | 0 | 100.0 ± 0.0 |
Excoecarianin | 0.1 | 91.6 ± 7.4 |
0.5 | 98.8 ± 2.1 | |
1.0 | 96.2 ± 6.6 | |
1.5 | 61.3 ± 7.8* | |
2.0 | 27.7 ± 7.9* | |
2.5 | 36.3 ± 10.8* | |
4.0 | 1.5 ± 0.1* | |
| ||
ACV | 0.5 | 100.0 ± 0.5 |
2.5 | 92.8 ± 6.5 | |
5.0 | 92.9 ± 4.9 | |
10.0 | 91.7 ± 8.2 |
Excoecarianin was mixed with HSV-2 at 37°C for 6 h before the residual viral titer was determined by plaque assay; Values were mean ± SD of three independent experiments; *P < .05 (compared between control and tested compound).