Table 2.
Flow cytometric analysis of normal, DMBA + croton oil, DMBA + croton oil + alcohol and DMBA + croton oil + drug-treated cells showing data of percentage of cells in different phases of cell cycle.
| Series | Cell-cycle analysis by FACS | |||
|---|---|---|---|---|
| SubG1 (%) | G1 (%) | S (%) | G2/M (%) | |
| Normal | 32.07 ± 0.375 | 32.73 ± 0.565 | 17.44 ± 1.24 | 2.14 ± 0.020 |
| DMBA + croton oil | 23.39 ± 0.005 | 23.56 ± 0.560 | 25.73 ± 0.610 | 6.625 ± 0.375 |
| DMBA + croton oil + alcohol | 22.15 ± 0.105 | 28.41 ± 0.410 | 28.74 ± 0.640 | 4.76 ± 0.040 |
| DMBA + croton oil + Sec cor 30 | 32.68 ± 0.310* | 31.88 ± 0.995* | 19.44 ± 1.16** | 2.18 ± 0.28*** |
Values are expressed as mean ± SE. Data are the means of the results from two independent experiments. Comparisons are made between carcinogen treated and drug fed mice. *P < .05, **P < .01; ***P < .001.