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. Author manuscript; available in PMC: 2012 Jul 14.
Published in final edited form as: J Med Chem. 2011 Jun 8;54(13):4923–4927. doi: 10.1021/jm200304y

Table 5.

PAMPA permeability results for fatostatin (1) and analogs 20 and 24

Compound PAMPA Papp (10−6 cm/sec) % Membrane retention Reference ID Reference PAMPA Papp (10−6 cm/sec) Reference % membrane retention
1 0.7555 94 Warfarin 4.11 0
20 1.059 93.95 Warfarin 5.34 0
24 14.98 97.35 Warfarin 5.58 0