Table 3.
| Table 3a. Characteristics of study population by SBP category, N=432 | ||||
|---|---|---|---|---|
| Systolic Blood Pressure* | ||||
| Characteristic† | <90th percentile (n=322) | ≥90th - <95th percentiles (n=49) | ≥95th percentile (n=61) | P-value for linear trend |
| Age, years | 11 ± 4 | 11 ± 4 | 10 ± 4 | 0.38 |
| Male | 59% (190) | 69% (34) | 59% (36) | 0.56 |
| Black race | 13% (41) | 24% (12) | 23% (14) | 0.01 |
| Hispanic Ethnicity | 14% (43) | 14% (7) | 15% (9) | 0.75 |
| Glomerular diagnosis | 19% (61) | 31% (15) | 28% (17) | 0.04 |
| Duration of CKD, years | 7 ± 5 | 6 ± 5 | 5 ± 4 | <0.01 |
| Iohexol GFR, ml/min/1.73m2 | 45 ± 15 | 43 ± 16 | 43 ± 14 | 0.26 |
| BMI percentile | 59 ± 30 | 61 ± 32 | 67 ± 29 | 0.08 |
| Obese, BMI >95th percentile | 15% (47) | 20% (10) | 26% (15) | 0.03 |
| Low birth weight, <2500g | 21% (65) | 18% (8) | 16% (10) | 0.35 |
| Premature birth, <36 weeks | 23% (73) | 23% (11) | 27% (16) | 0.61 |
| Parental history of hypertension | 27% (88) | 27% (13) | 34% (21) | 0.36 |
| Self-reported history of hypertension | 42% (134) | 61% (30) | 61% (37) | <0.01 |
| Proteinuria | ||||
| Significant, Up/c 0.2-2 | 60% (177) | 67% (32) | 60% (35) | 0.11‡ |
| Nephrotic, Up/c >2 | 13% (37) | 17% (8) | 17% (10) | 0.06‡ |
| Sodium (mmol/L) | 140 ± 2 | 139 ± 2 | 139 ± 2 | 0.14 |
| Potassium (mmol/L) | 4.5 ± 0.5 | 4.8 ± 0.6 | 4.5 ± 0.5 | 0.05 |
| Table 3b. Characteristics of study population by DBP category, N=432 | ||||
|---|---|---|---|---|
| Diastolic Blood Pressure* | ||||
| Characteristic† | <90th percentile (n=332) | ≥90th - <95th percentiles (n=41) |
≥95th percentile (n=59) | P-value for linear trend |
| Age, years | 11 ± 4 | 10 ± 5 | 9 ± 4 | <0.01 |
| Male | 58% (193) | 68% (28) | 66% (39) | 0.14 |
| Black race | 12% (41) | 27% (11) | 25% (15) | <0.01 |
| Hispanic Ethnicity | 13% (44) | 20% (8) | 12% (7) | 0.88 |
| Glomerular diagnosis | 22% (73) | 22% (9) | 19% (11) | 0.61 |
| Duration of CKD, years | 7 ± 5 | 6 ± 5 | 6 ± 4 | <0.01 |
| Iohexol GFR, ml/min/.73m2 | 45 ± 15 | 45 ± 18 | 42 ± 13 | 0.27 |
| BMI percentile | 59 ± 30 | 69 ± 29 | 64 ± 31 | 0.07 |
| Obese, BMI >95th percentile | 15% (51) | 23% (9) | 21% (12) | 0.17 |
| Low birth weight, <2500g | 20% (63) | 24% (9) | 19% (11) | 0.93 |
| Premature birth, <36 weeks | 24% (80) | 23% (9) | 19% (11) | 0.37 |
| Parental history of hypertension | 28% (92) | 32% (13) | 29% (17) | 0.72 |
| Self-reported history of hypertension | 45% (151) | 56% (23) | 46% (27) | 0.59 |
| Proteinuria | ||||
| Significant, Up/c 0.2-2 | 62% (187) | 67% (26) | 54% (31) | 0.38‡ |
| Nephrotic, Up/c >2 | 12% (37) | 13% (5) | 23% (13) | 0.03‡ |
| Sodium (mmol/L) | 140 ± 2 | 140 ± 2 | 139 ± 2 | 0.86 |
| Potassium (mmol/L) | 4.5 ± 0.5 | 4.6 ± 0.5 | 4.5 ± 0.4 | 0.90 |
Abbreviations used in table: BMI, body mass index; CKD, chronic kidney disease; GFR: glomerular filtration rate
*
Based on causal BP measurement at baseline visit and categorized according to reference 6.
†
Mean ± SD or percent (n);
‡
Compared to normal range Up/c (<0.2)