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. 2011 Jun 13;11:13. doi: 10.1186/1471-2415-11-13

Table 3.

Index therapy change within 6 months and full study period

Within 6 months Across full study period

Latanoprost
N = 632
Travoprost-Z
N = 268
Latanoprost
N = 632
Travoprost-Z
N = 268
Changed therapy, n % 134 (21.2) 77 (28.7) 218 (34.5) 121 (45.2)
 p-value* 0.0148 0.0026
Hazard ratio 1.519 1.499
 p-value 0.0035 0.0004
Days to change
 Mean ± SD 72.9 ± 51.2 54.1 ± 48.0 194.8 ± 192.9 178.0 ± 196.7
 Median 56.5 40.0 125.0 90.0

SD = standard deviation.

*Chi-square test.

The reference cohort is latanoprost. Based on the Cox proportional hazards model.