Table 5.

Adverse event(s) charted at index therapy change within 6 months and full study period among patients who changed, N (%)

	Within 6 months		Across full study period
	Latanoprost N = 134	Travoprost-Z N = 77	Latanoprost N = 218	Travoprost-Z N = 121
Hyperemia†	7 (5.2)	18 (23.4)	10 (4.6)	21 (17.4)
Burning	7 (5.2)	2 (2.6)	10 (4.6)	2 (1.7)
Pain/ocular discomfort	4 (3.0)	3 (3.9)	4 (1.8)	4 (3.3)
Blepharitis	3 (2.2)	2 (2.6)	4 (1.8)	2 (1.7)
Dry eye	1 (0.7)	1 (1.3)	3 (1.4)	4 (3.3)
Foreign body sensation	1 (0.7)	2 (2.6)	2 (0.9)	4 (3.3)
Pruritis	1 (0.7)	0	7 (3.2)	1 (0.8)
Other	8 (6.0)	8 (10.4)	16 (7.3)	10 (8.3)

*Reported by ≥2% of patients in either cohort at either time point. More than one event could be reported for each patient.

^†p < 0.0001 for both within six months and across full study period.