Table 3.
Findings of laboratory and clinical examinations*
| ALI/ARDS (n = 53) | CPE (n = 71) | Mixed (n = 23) | p value for ALI/ARDS vs CPE | |
|---|---|---|---|---|
| Laboratory findings | ||||
| WBC count, ×1000/μL | 10.4 (7.3-12.8) | 9.6 (7.2-13.4) | 9.8 (5.9-11.2) | 0.587 |
| CRP, mg/L | 119 (62-165) | 8 (2-42) | 100 (36-184) | < 0.001 |
| BNP, pg/mL | 202 (95-439) | 691 (416-1194) | 403 (221-1048) | < 0.001 |
| GFR, mL/min | 60.8 (28.6-92.9) | 46.0 (35.9-58.4) | 56.2 (29.7-86.9) | 0.056 |
| PaO2/FiO2 | 100 (68-147) | 111 (82-156) | 166 (9-220) | 0.322 |
| Mechanical ventilation | 34 (64) | 35 (49) | 9 (39) | 0.100 |
| APACHE II score | 17 (16-19) | 17 (16-18) | 17 (16-18) | 0.245 |
| Positive culture results | 28 (53) | 0 (0) | 0 (0) | -- |
| Chest radiography | ||||
| number of patients examined | 53 (100) | 71 (100) | 23 (100) | -- |
| infiltrates on two quadrants | 24 (45) | 38 (54) | 18 (78) | 0.468 |
| infiltrates on four quadrants | 28 (53) | 33 (46) | 6 (26) | 0.604 |
| pleural effusion | 43 (81) | 66 (93) | 19 (83) | 0.043 |
| cardiomegaly | 25 (47) | 39 (55) | 13 (57) | 0.500 |
| Echocardiography | ||||
| number of patients examined | 50 (94) | 71 (100) | 20 (87) | -- |
| LVEF, % | 60 (56-66) | 57 (45-69) | 49 (39-65) | 0.052 |
| mitral regurgitation ≥grade 2 | 15/50 (30) | 31/71 (44) | 7/23 (30) | 0.182 |
| right ventricular dilation | 13/50 (26) | 29/71 (41) | 8 (35) | 0.135 |
| Hemodynamics | ||||
| number of patients examined | 6 (11) | 4 (6) | 3 (10) | 0.206 |
| PCWP, mmHg | 10 (9-13) | 32 (28-37) | 32 (26-34) | 0.096 |
*Data are expressed as the number (%) or median (interquartile range).
ALI: acute lung injury; APACHE: acute physiology and chronic health evaluation; ARDS: acute respiratory distress syndrome; BNP: brain natriuretic peptide; CRP: C-reactive protein; CPE: cardiogenic pulmonary edema; GFR: glomerular filtration rate; LVEF: left ventricular ejection fraction; PCWP: pulmonary capillary wedge pressure