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. 2011 Jul 14;6(7):e21968. doi: 10.1371/journal.pone.0021968

Figure 4. CD103 is preferentially expressed by CD8 T cells in the intestinal epithelium as compared to the tumor.

Figure 4

Equal numbers of CD8 T cells from BALB/c-WT (WT, Thy1.1+) and BALB/c-CD103 KO (KO, Thy1.1+Thy1.2+) donors were adoptively transferred into a group of lethally irradiated A/J mice together with BALB/c-WT BMC plus SaI/N tumor cells. Recipient mice were sacrificed at days 7, 14, 21 and 28. Lymphocytes isolated from the indicated host compartments were then subjected to flow cytometric analyses. A. Mean percentage ± SEM (n = 5) of CD8 T cells in the intestinal epithelium (IEL closed circles) and the tumor (open circles) that expressed significant levels of CD103 at the indicated time points. B. Representative dotplot of CD103 expression by gated CD8+ cells in the intestinal epithelium (IEL) and tumor (TIL).