Table 1. Clinical and laboratory features of the subjects included in the study.
Characteristics | Non-HBV-infected Individualsn = 539 | Self-limited Infectionn = 205 | Persistent infection | ||||
Totaln = 496 | CHCn = 89 | IHCn = 101 | CHBn = 108 | LCn = 198 | |||
Age (years) | |||||||
Mean ± SD | 43.0±9.7 | 38.1±9.0 | 41.9±13.5 | 34.8±9.5 | 37.9±10.3 | 42.5±10.6 | 43.9±11.8 |
Gender (%) | |||||||
Female | 232 (43.04) | 61 (29.76) | 193 (38.91) | 38 (42.70) | 44 (43.56) | 46 (42.59) | 65 (32.83) |
Male | 307 (56.96) | 144 (70.24) | 303 (61.09) | 51 (57.30) | 57 (56.44) | 62 (57.41) | 133 (67.17) |
Liver function test (mean±SD) | |||||||
T-Bil (µmol/L) | 4.8±3.0 | 17.4±8.5 | 117.3±89.2 | 31.5±13.9 | 35.6±15.0 | 118.9±76.1 | 158.1±94.9 |
ALB (g/L) | 44.6±5.9 | 34.6±7.0 | 31.2±6.7 | 32.1±6.1 | 33.4±4.9 | 30.7±5.8 | 25.7±6.5 |
ALT (IU/L) | 26.7±11.4 | 27.1±9.8 | 161.1±95.5 | 30.7±10.4 | 32.4±15.9 | 263.8±180.4 | 160.9±118.1 |
AST (IU/L) | 16.4±11.0 | 33.0±13.6 | 128.8±107.4 | 27.7±11.9 | 29.8±10.6 | 160.5±122.5 | 136.6±101.8 |
GGT (IU/L) | 14.5±10.8 | 28.2±11.6 | 73.7±38.1 | 31.7±10.2 | 29.4±14.8 | 142.4±88.3 | 85.1±50.5 |
PT (seconds) | unknown | unknown | unknown | unknown | unknown | unknown | 24.2±6.6 |
HBV serum tests (%) | |||||||
HBsAg (+) | 0 | 0 | 496 (100) | 89 (100) | 101 (100) | 108 (100) | 198 (100) |
HBeAg (+) | 0 | 0 | 193 (38.91) | 89 (100) | 0 | 47 (43.52) | 57 (28.79) |
HBV-DNA (lg copies/mL) | 0 | 0 | 4.88±2.31 | 4.96±1.15 | 3.55±0.91 | 4.62±2.29 | 5.94±1.80 |
Method of diagnosis (%) | |||||||
Histology | 103 (20.77) | 12 (13.48) | 8 (7.92) | 22 (20.37) | 61 (30.81) | ||
CT or MRI | 80 (16.13) | 3 (3.37) | 5 (4.95) | 14 (12.96) | 58 (29.29) | ||
Ultrasonic | 496 (100) | 89 (100) | 101 (100) | 108 (100) | 198 (100) | ||
Child-Pugh score (%) | |||||||
Class A | 43 (21.72) | ||||||
Class B | 87 (43.94) | ||||||
Class C | 68 (34.34) |
ALB, albumin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CHB, chronic hepatitis B; CHC, chronic hepatitis B virus carrier; CT, computed tomography; GGT, γ-glutamyltransferase; HBV, hepatitis B virus; IHC, inactive hepatitis B surface antigen carrier; LC, liver cirrhosis; MRI, Magnetic resonance imaging; PT, prothrombin time; SD, standard deviation;. T-Bil, total bilirubin.