Table 5. rs430397 G>A polymorphism and cirrhosis risk in HBV patients.
Alleles/Genotypes | Noncirrhosisn = 298, (%) | Cirrhosisn = 198, (%) | OR (95%CI)* | P * |
G | 508 (85.23) | 304 (76.77) | 1 | |
A | 88 (14.77) | 92 (23.23) | 1.75 (1.26–2.42) | 0.001 |
GG | 218 (73.15) | 119 (60.10) | 1 | |
AG | 72 (24.16) | 66 (33.33) | 1.68 (1.12–2.51) | 0.011 |
AA | 8 (2.68) | 13 (6.57) | 2.98 (1.20–7.39) | 0.014 |
P-trend† | 0.005 |
*Pearson Chi-square test.
Multivariable logistic regression analysis adjusted with age and gender.