Table 3.

Association Between Depression and Functional Recovery Within 6 Months Following a Disabling Hospitalization.

	ADL Function						Mobility Function
	Unadjusted			Adjusted†‡			Unadjusted			Adjusted†‡
	Hazard Ratio	95% CI	p-value	Hazard Ratio	95% CI	p-value	Hazard Ratio	95% CI	p-value	Hazard Ratio	95% CI	p-value
Non-depressed	1.0	-	-	1.0	-	-	1.0	-	-	1.0	-	-
Depressed*	0.78	0.66, 0.94	0.03	0.91	0.75, 1.10	0.31	0.69	0.56, 0.86	<0.001	0.79	0.63, 0.98	0.03

ADL = Activities of Daily Living; CI = Confidence Interval

^*Between 58% to 85% of the participants who were depressed at any given face-to-face assessment prior to their disabling hospitalization were also depressed at their subsequent face-to-face assessment, for both the ADL and mobility samples, respectively.

^†The median (interquartile range) number of months between the face-to-face assessments and the index hospitalizations was 8 (4–13) and 9 (4–13) for the ADL and mobility samples, respectively. A total of 228 (36.6%) and 238 (38.1%) of the hospitalizations in the ADL and mobility samples, respectively, occurred within 6 months of the previous face-to-face assessment. An additional 227 (36.4%) and 206 (33.0%) of the hospitalizations in the ADL and mobility samples, respectively, occurred between 7 and 12 months following the previous face-to-face assessment.

^‡Adjusted for age, sex, race, education, number of chronic conditions, cognitive status, physical frailty, social support, antidepressant medication use, number of ADL or mobility tasks disabled prior to hospitalization, number of months between the depression assessment and the index hospitalization, and number of hospitalizations in each 18-month interval prior to the index hospitalization.