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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Cancer. 2011 Feb 1;117(15):3457–3467. doi: 10.1002/cncr.25884

Fig. 1. Treatment with SNDX-275 increases Fas expression on the surface of DLM8 cells and increases its sensitivity to FasL.

Fig. 1

(A) murine DLM8 cells were treated with 3 μM SNDX-275 for 24 h (dashed line), or 48 h (solid line), or left untreated (grey shading). Fas expression on the cell surface was detected using flow cytometry. (B) DLM8 cells were pretreated with 3 μM SNDX-275 for 24 h and then treated with 10 ng/ml soluble FasL for another 24 h. Untreated cells and cells treated with either agent were used as controls. The cell viability was detected by MTT assay.