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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Gene Ther. 2011 Apr 7;18(9):884–890. doi: 10.1038/gt.2011.33

Figure 4. Atoh1 delivery results in recovery of macular organ hair cell counts.

Figure 4

To determine the effects of IDPN and IPDN followed by atoh1 delivery, macular organ hair cell counts were taken on day 62 after treatment. Exposure to IDPN significantly decreases the number of hair cells in the utricle as well as in the saccule (light grey bars) in comparison to untreated controls (black bars). Delivery of Ad28GFAP.atoh1 into the perilymph after treatment with IDPN increased hair cell numbers significantly (dark grey bars) up to control levels.