Table 2.
HPV Viral Loads.Patients with HPV PCR positive samples shown.
| Patient | Sex | Age | Immunosuppression | Sample Code |
Histology | Site | DNA HPV Types | Viral Load |
Transcriptome Sequenced |
|||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HPV Type |
HPV Copies |
Input Cells |
HPV Copies/Cell |
|||||||||
| PC-021 | M | 89 | No | STA01-046 | KA | Scalp | FA7, FA127, FA37 | FA7 | ND | 3921 | ND | |
| FA37 | ND | 3921 | ND | |||||||||
| STA01-051 | KA | Scalp | HPV21, FA127, FA37 | HPV21 | ND | 13952 | ND | |||||
| FA37 | 100 | 13952 | 0.007 | |||||||||
| STA01-053 | Normal skin | Leg | HPV80, FA7 | HPV80 | ND | 6434 | ND | |||||
| FA7 | 28 | 6434 | 0.004 | |||||||||
|
| ||||||||||||
| PC-031 | M | 95 | No | STA01-130 | SCC | Scalp | - | |||||
| STA01-131 | Normal skin | Scalp | HPV5, HPV8 | HPV5 | 220872 | 2313 | 95.501 | |||||
| HPV8 | ND | 2313 | ND | |||||||||
|
| ||||||||||||
| PC-046 | M | 84 | No | STA01-068 | SCC | Hand | HPV75, FA108 | HPV75 | 149 | 14607 | 0.010 | |
| STA01-079 | Normal skin | Leg | HPV75 | HPV75 | 152 | 4651 | 0.033 | |||||
|
| ||||||||||||
| PC-003 | M | 68 | Heart Transplant | STA01-034 | SCC | Forehead | HPV5, HPV49, FAIMVS14 | HPV5 | 696 | 2611 | 0.267 | |
| STA01-122 | Normal skin | Cheek | - | Yes | ||||||||
|
| ||||||||||||
| PC-015 | F | 53 | Heart-Lung Transplant | STA01-018 | SCC | Arm | HPV9 | HPV9 | 984 | 28332 | 0.028 | Yes |
| STA01-076 | Normal skin | Arm | HPV9 | HPV9 | 57 | 33490 | 0.001 | Yes | ||||
| STA01-077 | KA | Arm | HPV9 | HPV9 | ND | 7264 | ND | Yes | ||||
| STA01-094 | Normal skin | Forehead | - | Yes | ||||||||
| STA01-095 | SCC | Forehead | - | Yes | ||||||||
|
| ||||||||||||
| PC-007 | M | 57 | Lung Transplant | STA01-074 | SCC | Scalp | HPV20, HPV21 | HPV20 | 1256 | 51462 | 0.024 | Yes |
| HPV21 | 10407 | 51462 | 0.202 | |||||||||
| STA01-078 | Normal skin | Scalp | HPV21, HPV20 | HPV20 | ND | 47880 | ND | |||||
| HPV21 | ND | 47880 | ND | |||||||||
|
| ||||||||||||
| PC-041 | M | 60 | Lung Transplant | STA01-029 | SCC | Cheek | HPV17 | HPV17 | 26132 | 45136 | 0.579 | |
| STA01-030 | SCC | Cheek | Sequence Not Obtained | Yes | ||||||||
|
| ||||||||||||
| PC-058 | M | 51 | Lung Transplant | STA01-010 | SCC | Lip | HPV5, HPV80, FA14 | HPV5 | ND | 6693 | ND | Yes |
| HPV80 | ND | 6693 | ND | |||||||||
| FA14 | 492 | 6693 | 0.074 | |||||||||
| STA01-045 | SCC | Cheek | FANIMVS11.4, FAIMVS11.3 | NA | ||||||||
| STA01-059 | SCC | Cheek | - | |||||||||
| STA01-132 | SCC | Scalp | - | |||||||||
| STA01-133 | Normal skin | Cheek | - | |||||||||
|
| ||||||||||||
| PC-030 | F | 73 | Renal Transplant | STA01-031 | KA | Leg | FA14, FA16.3 | FA14 | 28006 | 5098 | 5.494 | |
| FA16.3 | 1068 | 5098 | 0.209 | |||||||||
| STA01-032 | KA | Leg | FA16.3, FA75 | FA16.3 | ND | 17901 | ND | |||||
| STA01-090 | KA | Leg | FA14, HPV96, FA140.2, FA16.3 | FA14 | 17216 | 4712 | 3.654 | |||||
| FA16.3 | ND | 4712 | ND | |||||||||
| FA140.2 | ND | 4712 | ND | |||||||||
| STA01-091 | KA | Leg | FA16.3, FA140.2, FA14 | FA14 | 1808 | 3372 | 0.536 | Yes | ||||
| FA16.3 | 44140 | 3372 | 13.089 | |||||||||
| FA140.2 | 110 | 3372 | 0.033 | |||||||||
|
| ||||||||||||
| PC-054 | M | 55 | Renal/Pancreas Transplant | STA01-065 | SCC | Arm | - | |||||
| STA01-066 | SCC | Arm | HPV8 | HPV8 | 4462 | 25593 | 0.174 | Yes | ||||
|
| ||||||||||||
| PC-011 | M | 64 | CLL/SLL | STA01-064 | SCC | Forehead | HPV19, HPV49, FA123 | HPV19 | 1132 | 26360 | 0.043 | Yes |
| FA123 | 4717 | 26360 | 0.179 | |||||||||
| STA01-071 | SCC | Forehead | HPV19, FA33 | HPV19 | 38 | 3883 | 0.010 | |||||
|
| ||||||||||||
| PC-053 | M | 53 | HIV | STA01-099 | SCC | Forehead | HPV5, FA16 | HPV5 | 1126 | 32837 | 0.034 | Yes |
| PC-043 | M | 53 | No | STA01-035 | SCC | Hand | HPV16 | HPV16 | 570172 | 12156 | 46.904 | Yes |
| HPV8, FA51.2 | HPV8 | 3685 | 12157 | 0.303 | Yes | |||||||
| HeLa | F | HeLa | Cell Line | Cervix | HPV18 | HPV18 | 8496079 | 1350389 | 6.291 | Yes | ||
| ILS-19363 | F | 35 | No | ILS-19363-1 | SCC | Cervix | HPV16 | HPV16 | 3403823 | 1403307 | 2.426 | Yes |
ND: Not detected NA: No assay could be designed SCC: Squamous cell carcinoma KA: Keratoacanthoma MDS: Myelodysplastic syndrome ALL: Acute lymphoblastic leukemia CLL/SLL: Chronic lymphocytic leukemia/Small lymphocytic lymphoma SCT: Stem cell transplant GVHD: Graft vs. host disease.