Fig. 5.

Represents scatter plot diagram of Caspase-3 activity at the basal level (1.00) before culture [1.09(0.08–2.89)] and after 24 h culture under different condition, (2.00) neutrophils patients with sera of healthy control [1.69(0.62–3.14)], (3.00) cultured patients neutrophils with their own sera after addition of GM-CSF [2.09(0.24–6.57)], (4.00) Patients neutrophils with their own sera [12.21(1.67–52.17)], (5.00) cultured healthy neutrophils with patients sera [6.57(1.12–29.36)]. The difference was statistically significant (P < 0.001). The neutropenic patient’s sera induce the highest apoptotic effect on both patient neutrophil and healthy control neutrophil and addition of GM-CSF down regulate the apoptotic effect of patient’s sera