Figure 1.

(a) Experimental design for the dose-response study to evaluate the efficacy of the extract in protection against hypobaric hypoxia-induced transvascular leakage in rats. The animals from group (ii) to (vi) were exposed to hypoxia of 9144 m for 5 h in a decompression chamber. Eight animals were used in each group. (b) Experimental design for effective dose studies. The animals from group (ii) to (vi) were exposed to hypoxia of 9144 m for 5 h in a decompression chamber except VIth batch. Eight animals were used in each group.