Table 2.
Effect of C. asiatica on physical fitness measured by 30-s chair stand test and 6-min walk test.
Items | Pre-dose baseline score | Post-dose score | ||||
---|---|---|---|---|---|---|
1 month | 2 month | 3 month | Delay | |||
30-s chair stand test (times) | 16.05 ± 2.72 | 16.10 ± 3.67 | ||||
Placebo | 15.85 ± 2.87 | 15.65 ± 2.80 | 15.70 ± 2.99 | F(0.0500, 3.57) = 0.3352, | F(0.0500, 1.19) = 0.1351, | |
P = .7999 | P = .7172 | |||||
20.35 ± 4.82a,∗∗ | 18.60 ± 5.96 | |||||
CA250 | 16.85 ± 4.21 | 18.40 ± 4.07 | 18.35 ± 4.85 | F(0.0500, 3.57) = 5.2662, | F(0.0500, 1.19) = 2.2391, | |
P = .0028 | P = .1510 | |||||
20.35 ± 3.66b,∗∗ | 17.30 ± 4.03 | |||||
CA500 | 16.80 ± 4.36 | 17.75 ± 3.80 | 19.90 ± 4.10a,∗∗ | F(0.0500, 3.57) = 23.3794, | F(0.0500, 1.19) = 1.3768, | |
P < .0001 | P = .2551 | |||||
21.00 ± 4.48b,∗∗∗ | 17.90 ± 5.93 | |||||
CA750 | 16.80 ± 3.09 | 17.45 ± 3.53 | 18.55 ± 3.17a,∗ | F(0.0500, 3.57) = 13.9752, | F(0.0500, 1.19) = 0.9200, | |
P < .0001 | P = .3495 | |||||
| ||||||
6 min walk test (meters) | 518.35 ± 59.62 | 510.55 ± 78.06 | ||||
Placebo | 515.60 ± 42.18 | 509.45 ± 55.78 | 504.95 ± 57.32 | F(0.0500, 3.57) = 1.0645, | F(0.0500, 1.19) = 0.1759, | |
P = .3714 | P = .6796 | |||||
535.60 ± 52.40 | 519.25 ± 81.86 | |||||
CA250 | 517.60 ± 59.75 | 527.95 ± 42.34 | 524.25 ± 49.77 | F(0.0500, 3.57) = 1.6551, | F(0.0500, 1.19) = 0.0155, | |
P = .1869 | P = .9022 | |||||
521.35 ± 66.20 | 512.00 ± 67.95 | |||||
CA500 | 509.50 ± 57.38 | 517.00 ± 64.62 | 523.10 ± 67.8 | F(0.0500, 3.57) = 1.8655, | F(0.0500, 1.19) = 0.0355, | |
P = .1457 | P = .8526 | |||||
524.75 ± 80.68 | 520.55 ± 87.65 | |||||
CA750 | 511.75 ± 54.12 | 517.80 ± 75.67 | 529.05 ± 82.27 | F(0.0500, 3.57) = 1.2784, | F(0.0500, 1.19) = 0.5046, | |
P = .2905 | P = .4861 |
Subjects were measured physical fitness measured by 30-s chair stand test and 6-min walk test. Data are presented as mean ± SD. P- and F-values were compared between pre-dose baseline score and post-dose 1, 2, 3 month and 1 month after cessation of treatment (n = 20/group).a, b P-value <.01 and.001 compared with pre-dose baseline score, respectively.
*, **, ***P-value <.05, .01 and .001 compared with placebo treated group, respectively.