Table 2.

Associations of High Uric Acid Level (>7 mg/dL) and BMI, WHR, Waist Circumference Categories, and Weight Gain

	Cases	OR1a	(95% CI)	OR2b	(95% CI)
BMI
Quintile 1	142	1.00		1.00
Quintile 2	156	1.27	0.99–1.64	1.12	0.86–1.46
Quintile 3	188	1.64	1.27–2.10	1.35	1.03–1.76
Quintile 4	236	2.56	1.99–3.29	2.01	1.53–2.65
Quintile 5	274	3.23	2.50–4.17	2.35	1.75–3.16
		P trend <0.001		P trend <0.001
WHR
Quintile 1	124	1.00		1.00
Quintile 2	131	1.29	0.98–1.70	1.11	0.84–1.47
Quintile 3	244	2.00	1.56–2.55	1.58	1.22–2.05
Quintile 4	217	2.34	1.82–3.03	1.77	1.34–2.33
Quintile 5	280	2.84	2.21–3.65	1.92	1.44–2.56
		P trend <0.001		P trend <0.001
Waist circumference
Quintile 1	144	1.00		1.00
Quintile 2	138	1.23	0.95–1.60	1.11	0.85–1.46
Quintile 3	183	1.77	1.38–2.28	1.51	1.14–2.01
Quintile 4	238	2.46	1.93–3.15	1.97	1.44–2.68
Quintile 5	293	3.16	2.47–4.06	2.27	1.56–3.30
		P trend <0.001		P trend <0.001
Standardized weight gain
≤0 kg/5 year	72	1.00		1.00
0–0.6 kg/5 year	58	1.38	0.93–2.05	1.26	0.85–1.88
0.6–1.7 kg/5 year	193	1.82	1.33–2.48	1.55	1.13–2.14
1.7–2.8 kg/5 year	222	2.14	1.56–2.93	1.67	1.19–2.34
>2.8 kg/5 year	371	3.73	2.72–5.12	2.71	1.90–3.85
	P trend <0.001			P trend <0.001

^aOR1: Adjusted for age, kcal/day, physical activity, alcohol consumption, smoking, education level, income level, occupation, hypertension medication, hypertension, and pre-existing CVD. For standardized weight gain analysis we included weight at 20 years in the model as well.

^bOR2: As above plus WHR for BMI and standardised weight gain analysis and BMI for WHR and waist circumference analysis.

Abbreviations: BMI, body mass index; WHR, waist-to-hip ratio; OR, odds ratio; CI, confidence interval; CVD, cardiovascular disease.