Table 1.
Physiological Parameters in the Tempol Series
| |
|
Measurement period |
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|---|---|---|---|---|---|---|---|---|
| Variable | Group | Pre-injury | 1 h | 2 h | 3 h | 4 h | 5 h | 6 h |
| MAP (mm Hg) | 1 | 109±2 | 102±4 | 106±2 | 108±4 | 103±4 | 104±2 | 102±4 |
| 2 | 103±4 | 96±1 | 98±2 | 99±3 | 99±3 | 96±2 | 97±2 | |
| 3 | 108±5 | 106±2 | 101±3 | 103±3 | 107±3 | 105±5 | 107±3 | |
| 4 | 107±3 | 103±1 | 100±1 | 101±2 | 97±3 | 97±2 | 101±2 | |
| pH | 1 | 7.42±0.01 | 7.40±0.01 | 7.40±0.01 | 7.39±0.01 | 7.40±0.01 | 7.38±0.01 | 7.38±0.01 |
| 2 | 7.40±0.01 | 7.41±0.01 | 7.41±0.01 | 7.41±0.01 | 7.41±0.01 | 7.40±0.02 | 7.41±0.01 | |
| 3 | 7.41±0.01 | 7.40±0.01 | 7.40±0.01 | 7.38±0.01 | 7.39±0.01 | 7.40±0.01 | 7.40±0.01 | |
| 4 | 7.39±0.01 | 7.41±0.01 | 7.39±0.01 | 7.39±0.01 | 7.39±0.01 | 7.41±0.01 | 7.40±0.01 | |
| Pao2 (mm Hg) | 1 | 90±1 | 92±3 | 90±4 | 91±3 | 91±1 | 90±3 | 90±3 |
| 2 | 85±4 | 85±4 | 85±3 | 88±7 | 88±7 | 90±4 | 86±5 | |
| 3 | 94±5 | 90±5 | 88±4 | 88±3 | 87±1 | 88±2 | 92±1 | |
| 4 | 83±6 | 85±4 | 106±3a | 78±3 | 78±3 | 87±5 | 86±3 | |
| Paco2 (mm Hg) | 1 | 37±1 | 36±1 | 36±1 | 38±1 | 38±1 | 38±1 | 37±1 |
| 2 | 39±1 | 36±1 | 36±1 | 36±1 | 36±1 | 36±1 | 36±1 | |
| 3 | 37±1 | 37±1 | 38±1 | 38±1 | 38±1 | 37±1 | 36±1 | |
| 4 | 39±1 | 38±1 | 38±1 | 37±1 | 37±1 | 36±1 | 36±1 | |
a
Significant difference compared with the values of groups 1, 2, and 3 at same measurement point (p<0.05).
Values are expressed as the mean±standard error of the mean (SEM).
MAP, mean arterial blood pressure; Pao2, arterial oxygen tension; Paco2, arterial carbon dioxide pressure.