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rVSMC migration. (a) Concentration-dependent response of Ang-II-induced rVSMC migration. (b) 3,4-di-O-caffeoylquinic acid dose-dependently inhibited 100 nM Ang-II-induced migration. *P < .01 and **P < .001, significant difference versus samples treated with Ang II alone. Each histogram represents the mean ± SE of three separate experiments run in triplicate on four separate cultures.
