| Family history of diabetes* | |||
|---|---|---|---|
| Presence (+) | Absence (-) | P value | |
| Number of subjects | 13 | 17 | |
| Age, years | 24.8±2.7 | 24.5±1.9 | NS |
| BMI, kg/m2 | 21.2±3.4 | 22.3±3.6 | NS |
| Waist circumference, cm | 73.8±12.6 | 78.1±10.8 | NS |
| HOMA-R | 1.1±0.9 | 1.2±0.6 | NS |
| HOMA-β, % | 64.3±49.8 | 71.4±43.4 | NS |
| Insulinogenic index | 0.8±0.5 | 0.8±0.5 | NS |
| IRI-AUC0-120, μU h/mL | 3840.2±1493.0 | 4398.4±2321.5 | NS |
*Defined as subjects with first- to third-degree relatives with T2DM.
AUC=area under the curve; BMI=body mass index; HOMA-R=homeostasis model assessment for insulin resistance;
HOMA-β=homeostasis model assessment for insulin secretion; IRI=immunoreactive insulin; NS=nonsignificant;
T2DM=type 2 diabetes mellitus