Table 6.
Evolutionary rates for complete genome, non CURS-Core region and CURS-Core region estimated from the combined genotype data sets.
| Strict Clock | UCLD Relaxed Clock | ||||
|---|---|---|---|---|---|
| Mean | 95% HPD | UCLD Mean | 95% HPD | ||
| Within-host HBeAg +ve |
complete genome | 2.58E-05 | 1.53E-05–3.74E-05 | 4.77E-05 | 2.55E-05–7.94E-05 |
| non CURS-Core | 2.62E-05 | 1.52E-05–3.76E-05 | 4.81E-05 | 2.47E-05–7.95E-05 | |
| CURS-Core | 2.49E-05 | 1.26E-05–3.68E-05 | 4.67E-05 | 2.06E-05–7.77E-05 | |
| Within-host HBeAg −ve |
complete genome | 1.09E-04 | 8.13E-05–1.39E-04 | 1.24E-04 | 8.71E-05–1.62E-04 |
| non CURS-Core | 8.61E-05 | 6.35E-05–1.09E-04 | 9.72E-05 | 6.85E-05–1.31E-04 | |
| CURS-Core | 1.79E-04 | 1.21E-04–2.35E-04 | 2.02E-04 | 1.37E-04–2.72E-04 | |
| Among-host HBeAg +ve |
complete genome | 5.99E-05 | 2.32E-05–9.92E-05 | 6.31E-05 | 2.20E-05–1.00E-04 |
| non CURS-Core | 6.24E-05 | 2.27E-05–1.02E-04 | 6.58E-05 | 2.30E-05–1.05E-04 | |
| CURS-Core | 5.23E-05 | 1.87E-05–8.66E-05 | 5.50E-05 | 2.01E-05–8.96E-05 | |
| Among-host HBeAg −ve |
complete genome | 1.95E-04 | 1.89E-05–3.36E-04 | 2.00E-04 | 6.32E-05–3.42E-04 |
| non CURS-Core | 1.78E-04 | 2.34E-05–3.13E-04 | 1.83E-04 | 5.38E-05–3.08E-04 | |
| CURS-Core | 2.44E-04 | 2.60E-05–4.29E-04 | 2.51E-04 | 6.91E-05–4.25E-04 | |