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. 2011 Mar 11;183(12):1680–1688. doi: 10.1164/rccm.201002-0254OC

Figure 1.

Figure 1.

Predicted probability of chronic beryllium disease (CBD) by HLA-DPB1 E69 (glutamic acid at position 69) genotype and lifetime-weighted average exposure based on weighted logistic regression using predictors described in Table 6. Regression weighted using previously documented Rocky Flats site-wide CBD prevalence of 1.7% (10). HLA-DPB1 E69− = carriage of only non–E69-containing alleles; single HLA-DPB1 *02 allele = carriage of one E69-containing *02 allele and one non–E69-containing allele; single HLA-DPB1 E69+ non-*02 allele = carriage of one E69-containing non–*02 allele and one non–E69-containing allele; E69 homozygote = carriage of one E69-containing non–*02 allele and one E69-containing *02 allele; Composite = average site-wide probability of CBD assuming the HLA-DPB1 characteristics of our case–control participants are representative of the site population.